The data concerning the class II antigens of this panel are the most interesting. However, although agreement with the EULAR recommendations is high, many barriers prevent their implementation in clinical practise, including lack of timely referral to rheumatologists; suboptimal use of synthetic DMARDs; poor access to biologics; lack of awareness of the burden of RA among healthcare professionals, patients and payers; and lack of appropriate staffing levels.To optimise the management of RA in the Middle East and Africa, will require a multi-pronged approach from a diverse group of stakeholders-including local, national and regional societies, such as the African League of Associations in Rheumatology and International League of Associations for Rheumatology, and service providers-to collect data on the epidemiology and burden of the disease; to increase awareness of RA and its burden among healthcare professionals, payers and patients through various educational programmes; to encourage early referral and optimise use of DMARDs by promoting the EULAR treatment recommendations; to encourage the development of locally applicable guidelines based on the EULAR treatment recommendations; and to facilitate access to drugs and the healthcare professionals who can prescribe and monitor them. In addition, the effects of HEAC on liver and renal function parameters as well as its effect on the antioxidant enzyme system were investigated. Conclusion: We postulate that countries’ developmental status and their geographical and geomagnetic location influence the age of RAO. Objective. A similar hypothesis has been suggested for hyperuricemia and gout. Objectives Rheumatology in Burkina Faso is booming. Our study confirmed the findings of others that rural African groups have extremely low rates of RA. Th cell can differentiate into at least four distinct subpopulations comprising Th1, Th2, Th17, and T regulatory (Treg) cells. Among the 23/38 patients with DOCGL 4–10, inflammation was rated as explaining 41%–10%% of DOCGL in 6/23 (29%), versus 10/23 (43%) for damage, and 5/23 (22%) distress. They have been reported, however, in patients with little arthritis and no systemic disease. It is a crippling disease, which causes widespread invalidism, but seldom kills. Our study focuses on the development and implementation of FCM-based DSS for RMD diagnosis (RMD-FCMDSS). ESR (mm/hr)† The aim of this study was to describe the phenotype and genotype of rheumatoid arthritis (RA) in Congolese patients. Such marked differences in genetically closely related communities point to the importance of sociological and environmental factors in the pathogenesis of rheumatoid arthritis. 3. Age (years)† Secondary Methods Introduction Adelowo et al. ... McGill observed an increasing frequency of RA and Systemic Lupus Erythematosus (SLE) among East, Central, and South Africa [23]. The information in this study would serve as a predictive index for the onset of Rheumatoid arthritis. They all fulfilled the 1987 American College of Rheumatology (ACR) revised …. The cells were washed in phosphate-buffered saline (PBS) and suspended in a small amount of PBS. Similarly, the relationship between RF and gender showed that 5.5% (n=101) of females were positive while than 3.8% (n=81) of males were positive. Rheumatoid arthritis is not uncommon among Nigerian; and clinical, serologic acumen are necessary for early diagnosis and appropriate referral. Rheumatoid factors (RF) were positive in 21 out of 30 patients (70.0%). The frequency of osteoarthritis was 19.70 % (804 cases) with a predominance of knee osteoarthritis (657 cases). Rheumatology services are limited or non-existent in many parts of sub-Saharan Africa. Statistical analysis was performed using Statistical Package for Social Sciences (SPSS) version 20 (IBM Corp.; Armonk, NY, USA). The profile of rheumatologic diseases in Burkina Faso, after 5 years of practice, confirms the diversity and importance of these conditions dominated by a degenerative pathology of the spine and limbs, including infectious diseases such as Pott's disease and the inflammatory and metabolic diseases. Primary care delay is defined as from the first primary care presentation to referral to rheumatology. Initial therapy of the major rheumatological diseases is with analgesics, such as paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs). In the United States, a Centre for Disease Control (CDC), survey based on data from 2007 -2009 revealed that 22.2% (49.9 million) of adults aged ≥ 18 years had self-reported doctor-diagnosed arthritis, and 9.4% (21.1 million or 42.4% of those with arthritis) had arthritis-attributable-to-activity-limitation (AAAL) and with an aging population this figure is expected to rise (Woolf and Pfleger, 2003; Centers for Disease Control and Prevention, 2010). All cited references read in full. Participation was voluntary, and respondents were assured that the information obtained was strictly for research and academic purposes only and were guaranteed the liberty to opt out from the study at their own convenience. A total of 42 cases of ocular diseases were found in 23 (46%) patients. Most of these factors are likely to be associated with both disease occurrence and severity. The goal of treatment is to limit pain … 8. RA was rare in rheumatologists should be the lead physicians in patients with RA. phenomenon had a slightly higher prevalence of vasculitis than the subgroup without Raynaud's phenomenon. A study from Congo suggested that the condition may be less severe in some African populations [21], whereas a study in Nigeria found extra-articular manifestations in just under one-third of patients. No patients had had a biotherapy agent. Early aggressive treatment with immunosuppressives is indicated. Unit of Brest University, Rheumatoid arthritis (RA) is a worldwide inflammatory joint disease with variable degrees of joint damage and extra articular manifestations (EAMs). Congolese patients with RA consult long after disease onset. This disease affects men and women, […] Medical School. 11 (36.7) Rheumatism” is derived from the Greek word “rheuma,” which means a swelling. was retrospectively obtained from the standardized clinical records of 322 RA in-patients first admitted to the Rheumatology Drugs for the treatment of Arthritis and Rheumatism in Nigeria, Can I use bitter kola to stop spitting and vomiting in…. is high in French RA in-patients, and that some clinical and biological abnormalities (vasculitis, low CRP level and low C4 Patients vary in their response to treatments for arthritis. Northern countries report an age of RA onset of around 50 years, but apparently, variability exists across different geographical regions. In addition, a "classification tree" schema is presented which performs equally as well as the traditional (4 of 7) format. In a proof-of-concept cross-sectional worldwide survey, rheumatologists from preselected cities interviewed 20 consecutive RA patients regarding the date of RA onset (RAO, when the patient first noted a swollen joint). The treatment generally offered by veterinarians consisted in reducing the physical activity of the animal to relieve the joints (exits on a leash, short walk, no significant effort, avoid going down and up the stairs). 12 (25.0) In the future, more rigorous studies made possible by increased access to health care will provide improved insight into the semiology and epidemiology of bone and joint diseases in this area. Two copies were found in one patient (2.7%) and in one control (4.2%). Rheumatoid arthritis is caused by the immune system attacking the joints as if they were foreign tissues. age 75 yr, and fell in the very elderly. They have been reported, however, in patients with little arthritis and no systemic disease. Criteria 1 through 4 must have been present for at least 6 weeks. Materials and Methods British black African patients had significantly more tender joints and disability. Analysis was restricted to controls, low and moderate DAS28 groups (we do not report data for high DAS28) because the relatively low number of RA patients with high DAS28 scores limited statistical reliability. Among the rural Blacks only 1 respondent had definite RA and 6 had probable RA, giving a prevalence of 0,87% for combined definite and probable RA. 29 (96.7) Weight was measured in the upright position to the nearest 0.1 kg using a calibrated balance beam scale. Gout was the most common inflammatory joint disease seen in inpatients in West Africa and Equatorial Africa. Prolonged use of steroids can cause stomach ulcer and a condition called Cushing’s syndrome. Cases of RA were defined Among the urban group 5 respondents had definite RA and 13 had probable RA, a combined prevalence of 3,3%. Methotrexate (MTX) is an effective disease modifying antirheumatic drug (DMARD) with a relatively safe profile, and it is widely used to treat neoplastic diseases and dermatologic and rheumatologic disorders. Globally, increasing demand for rheumatology services has led to a greater reliance on non-physician healthcare professionals (HCPs), such as rheumatology nurse specialists, to deliver care as part of a multidisciplinary team. Mr. Usman 68 Years old patient from Nigeria undergone successful stem cell therapy treatment in India for Rheumatism problem he has been suffering from years he thanked MedAcess for curing his disease via stem cell therapy at an affordable cost Pathological degrees of state and trait anxiety were found among 7 (14%) and 5 (10.4%) patients respectively. 👉Radiological investigations like X-rays. A comparative study of fertility in Nigerian women with and without rheumatoid arthritis, Musculoskeletal symptoms and non-prescribed treatments are common in an urban African population of people living with HIV, Decision support system for diagnosing Rheumatic-Musculoskeletal Disease using fuzzy cognitive map technique, Delayed diagnosis and treatment of rheumatoid arthritis in Sarawak General Hospital, Digital technology: The key to unlock rheumatology in Africa, Nurse-led care for the management of rheumatoid arthritis: a review of the global literature and proposed strategies for implementation in Africa and the Middle East, Clinical spectrum of rheumatologic diseases in a department of rheumatology in Ouagadougou (Burkina Faso), Challenges and opportunities in the early diagnosis and optimal management of rheumatoid arthritis in Africa and the Middle East. Infertility is not uncommon among patients with RA, and like many aspects of rheumatic diseases, it may have been under-recognized in the Nigerian patients. In vitro antioxidant and anti-arthritic effect of the aqueous and ethanolic leaf and root bark extract of Alafia barteri, Pattern of systemic lupus erythematosus among Nigerians, Rheumatoid arthritis in blacks in South Africa, The incidence of rheumatoid arthritis in the United Kingdom: results from the Norfolk Arthritis Register, Rheumatic disorders in Sub-saharan Africa, Clinical and radiological features of rheumatoid arthritis in British black Africans, Rheumatoid arthritis and connective tissue disorders: sub-Saharan africa, AFPL-16. We studied four such patients, in whom (1) RF was present in high titer; (2) nodules were often extensive (nodulosis) and involved elbows, hands, and feet, with a predilection for tendons; and (3) roentgenograms showed large, subchondral bone cysts without cortical erosion or correlation with nodule location. Objective: © 2008-2021 ResearchGate GmbH. The participants were aged 18 years or older. Methods. Radiographs were scored according to Sharp-van der Heijde. Arthritis is most commonly seen in adults over the age of 65, but it can also develop in children, teens, and younger adults. The proportion of IgM-RF positivity was lower among Sudanese patients with RA (52.4% vs 75.5%, p < 0.0001). Outpatients with RA from Sudan (n = 281) and Sweden (n = 542) diagnosed according to the 1987 American College of Rheumatology criteria were recruited between December 2008 and September 2010 and compared … Below you can find some medications used in rheumatism treatment: Nonprescriptive oral analgesics like acetaminophen and prescriptive narcotics such as oxycodone and hydrocodone which are not affecting causes of disease; Topical analgesics; NSAIDs (non-steroidal anti-inflammatory drugs) like Ibuprofen, naproxen sodium and COX-2 inhibitors. In the rural community such changes as were encountered were invariable mild and no-one had clinical features resembling classical rheumatoid arthritis; by contrast, among the urban Blacks the changes resembled those of rheumatoid disease in White populations. To assess the levels of state and trait anxiety and determine their relationships with perceived social support among Nigerian patients with rheumatoid arthritis (RA). Following multiple regression analysis, the predictors of the presence of ocular manifestations were age greater than 45 years and positive anti-citrullinated protein antibody. 👉Swelling are the most common. The minor allele frequencies (MAF) were tightly correlated between Cameroonian controls and YRI individuals (correlation coefficient 93.8%, p = 1.7E-13), and they were pooled together. In Nigeria, for example, the mean time to presentation to a rheumatologist is 63 months from first symptoms due to delays in diagnosis, ignorance on the part of medical and nursing personnel previously consulted by patients and misconceptions about the diagnosis and management of RA, ... As in most countries with scarce resources in sub-Saharan Africa, paraclinical exams, especially immunological exams are not always available in Togo to diagnose RA. • View inline Therefore, African countries will increasingly be a continued valuable source of clinical material for comparative studies to help elucidate factors that influence the development of rheumatic diseases. There were 34 women and 8 men. A Caucasian aggregate genetic-risk score (GRS) was calculated as the sum of the weighted risk-allele counts. Treatment was initiated with immunosuppressives, steroids, anti epileptics, aspirin and anti hypertensives as indicated. Early diagnosis and treatment of RA to achieve tight control of the disease will improve outcome and prevent disability. Health Benefits of ginger, garlic, turmeric and cloves combo plus Side... 120 Nigerian foods for Diabetics: managing diabetes in Nigeria. This is the primary goal of treatment of all forms of rheumatism associated disorders whether they are inflammatory or non-inflammatory. Conclusion: A positive history of infertility was found in 22 (44%) patients and 14 (28%) controls (p=0.096), while 17 (34%) patients and 23 (46%) controls were found to be postmenopausal (p=0.221). Standardized protocols and assessment criteria were used to study 84 black patients with no non-Bantu antecedents and 84 UK Caucasian patients with RA (matched for disease duration, sex and age). The anti-arthritic activity of HEAC was assessed based on the ability of HEAC to alter the paw edema diameter, body weight, full blood count, renal and liver function markers, glycoprotein, lysosomal enzymes and possible antioxidant potential in the arthritic rats. Objectives The proportion of patients seen in the rheumatology clinic with RA is higher than that reported from Zambia (4.7%) 15 and Democratic Republic of Congo (8.5%) 10 but significantly less than those reported from South Africa (52%) 16 and Kenya (37.3%) 17 . The new criteria demonstrated 91-94% sensitivity and 89% specificity for RA when compared with non-RA rheumatic disease control subjects. A high index of suspicion is needed for this otherwise severe disease in blacks. The association was not significant at p-value of 0.05. To compare clinical characteristics and treatment between simultaneously investigated Sudanese and Swedish outpatients with rheumatoid arthritis (RA). Random sampling from the UK cohort showed that this difference in association is unlikely to be explained by small sample size or chance, but is statistically significant with p<0.001. 📌Another common form of arthritis is Rheumatoid Arthritis an autoimmune disorder. Several studies have shown that the disease is less severe and has fewer EAMs in Mediterranean countries than in other geographical areas.1–3 In Lebanon, there are no reliable data on its characteristics. 2 (4.2) Married Specialist management: Needs and benefits. 18 (37.5) The average duration of the disease was 86.17 ± 82.01 months with extremes of 8 and 360 months. As such, rheumatoid factor levels in blood could serve as a predictive index for the onset of Rheumatoid arthritis. to relate this symptom to clinical, radiological and serological characteristics of the patients. Studies in this area have tended to be hypothesis testing rather than generating new etiologic or related hypotheses. Acute and chronic locomotor problems associated with diverse entities such as leprosy, brucellosis, meningococcus, alpha viruses, parasites, fluorosis, rickets and haemoglobinopathies enhance diagnostic diversity and therapeutic and educational requirements. it lowers blood cholesterol level. Height was measured (subjects stood erect, barefoot, with feet together, looking forward) to the nearest 0.1 m using a measuring tape. Three (5.5%) of 55 individuals tested were positive for rheumatoid factor, a rate lower than in previous surveys of rural West African populations. We suggest that nodulosis, bone cysts, and elevated RF with little active arthritis constitute a relatively benign variant of rheumatoid disease. Rheumatologists have an in-depth understanding of new assessment methods to optimize medical treatment and to make best use of and co-ordinate multi-disciplinary care. Part I. Rheumatoid arthritis and ankylosing spondylitis. Infectious diseases were prevalent as a result of underindustrialization and defective hygiene. HBOT is a superior treatment for RA. Disease modifying anti-rheumatic drugs (DMARDS) delay is defined as from the rheumatology clinic appointment to starting DMARDS. The conditions of three of these patients had been previously misdiagnosed as gout or xanthoma. Questionnaires were administered to obtain sociodemographic data from the participants. 13 (27.1) All new cases A cross-sectional study of 50 patients satisfying the 2010 American College of Rheumatology/European League against Rheumatism Classification Criteria for RA was conducted. The association was not significant. Laboratory tests and radiographic investigations were carried out. [16] indicated paucity of data on RA among the African population, highlighting the need for more RA-related research in the African context. Rheumatism Treatment near me - Get Quotes, Compare prices, work experience, ratings, reviews, hire a pro. Written informed consent was obtained from all participants who opted to participate after the aims and objectives of the study had been explained to them. Keratoconjunctivitis sicca was found in 15 (30%) patients; cataract, 13 (26%); scleritis/episcleritis, 4 (8%); disk edema, 4 (8%); glaucoma, 3 (6%); ulcerative keratitis, 1 (2%); vitreitis, 1 (2%); and macula edema, 1 (2%) patient. 👉Stiffness Objective: The average ESR and DAS28 scores among the RA cases were 35.50 (29.25-55.25) mm/hr and , respectively. Altogether 1352 subjects over the age of 15 years were examined clinically and radiologically; serological tests for rheumatoid factor (RF) were carried out in 920. HAQ-DI correlated strongly with both STAI-S (r = 0.735, p ≤ 0.001) and STAI-T (r = 0.575, p ≤ 0.001) but not with ISEL. However, the interplay of their cytokine pattern is minimally explored. Briefly, the whole blood was poured into the Ficoll-containing tubes and centrifuged at 1500 rpm for 30 min at 4°C with no brakes. Our results show the value of population studies in the investigation of the relationship between the different HLA class II antigens.